phages for extremophiles?
Oladele A. OGUNSEITAN
oaogunse at UCI.EDU
Sat Apr 5 20:02:40 EST 1997
Several virus genomes are known to interact with the protein coat
in a way that may afford stability in harsh environmental conditions.
Perhaps interactions similar to histone-DNA associations exist between
hyperthermophilic phage genomes and external protein coat?
- Dele Ogunseitan
University of California at Irvine
On 5 Apr 1997, Whitney J wrote:
> Penguin (penguin at navix.net) spake thus:
> > Primarily,
> > extemophiles tend to also be members of the Archaea. Of the archaea,
> > the acidophilic hyperthermophile Sulolobus has been found to have
> > several [phages], as reported by W. Zillig et al.
> Recently, I've been doing literature research, trying to find information
> on how hyperthermophiles keep their genomes stable at high temperatures.
> I haven't found much information, but what I have found implies that
> protein interaction (positive toroidal supercoiling around histone-like
> structures) is required. Has anyone postulated how would a
> hyperthermophilic phage would keep its genome stable?
> --Whitney Fraser
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