phages for extremophiles?

Oladele A. OGUNSEITAN oaogunse at UCI.EDU
Sat Apr 5 20:02:40 EST 1997

	Several virus genomes are known to interact with the protein coat 
in a way that may afford stability in harsh environmental conditions.  
Perhaps interactions similar to histone-DNA associations exist between 
hyperthermophilic phage genomes and external protein coat?

- Dele Ogunseitan

University of California at Irvine 

On 5 Apr 1997, Whitney J wrote:

> Penguin (penguin at spake thus:
> > Primarily,
> > extemophiles tend to also be members of the Archaea.  Of the archaea,
> > the acidophilic hyperthermophile Sulolobus has been found to have
> > several [phages], as reported by W. Zillig et al.
> Recently, I've been doing literature research, trying to find information 
> on how hyperthermophiles keep their genomes stable at high temperatures.  
> I haven't found much information, but what I have found implies that 
> protein interaction (positive toroidal supercoiling around histone-like 
> structures) is required.  Has anyone postulated how would a 
> hyperthermophilic phage would keep its genome stable?
> --Whitney Fraser

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