Broad Host Range Bacteriocins/colicins

Michael Benedik benedik at
Wed Feb 26 18:50:32 EST 1997

Is anyone aware of any bacteriocins / colicins / microcins which have
fairly broad host range (for example not just enterics, but many Gram
negs) that act in the cytoplasm? I am not interested in membrane
disrupting microcins, but rather those which need to be transported
into the cytoplasm to act (like colicin E9 which is a nuclease). 

Thanks for any pointers to interesting molecules.

Michael Benedik
Department of Biochemical Sciences
University of Houston
benedik at

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