H.pylori primary metronidazole resistance

Frank Eldredge bime at ix.netcom.com
Tue Jan 14 11:03:45 EST 1997


In article <5b61am$8uf at neptune.worldonline.nl>,
	magdrian at worldonline.nl (A.Talens) wrote:

>Primary metronidazole resistance in H. pylori seems to be rapidly
>increasing in many parts of the world. Has anyone got a comprehensive
>explanation for this phenomenon ?
>
>Dr. A.A. van Zwet
>
>

 Probably due to high rate of random mutations available
in H. pylori.  The increased use of this drug will also
increase the selective pressure in favor of these
resistance mutants.

Cheers,


F. A. Eldredge, PhD




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