tburmei at gwdg.de
Tue Mar 18 03:42:40 EST 1997
In article <332D0BB7.48E3 at pasteur.fr>, onamy at pasteur.fr wrote:
> does anybody know, how spectinomycin act?
> thnaks for your help
> olivier Namy (france)
Spectinomycin is a aminoglycoside-antibiotic. it is obtained from
cultures of Streptomyces spectabilis (a fungus). It acts - like all
aminoglycosides - by binding to bacterial ribosomes (small spheric
particles that are essential for protein synthesis in the bacterium).
It has a primarily bactericidal effect.
The main field of application is against penicillin-resistant gonococci
(or if the patient with gonorrhoea has a penicillin allergy).
Thomas Burmeister (Germany)
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