Domains & Motifs?
lloyd.graham at molsci.csiro.au
Thu Oct 30 01:53:53 EST 1997
In article <34566887.992007 at news.hku.hk>, dicklai at usa.net (Dick Lai) wrote:
> HI all,
> What's the different between "Domains" and "Motifs"? Thanks!
> Best Regards,
> Dick Lai
> E-mail:dicklai at usa.net
In addition to features mentioned in the previous replies, a key
distinction is size. A domain is a portion of polypeptide chain, usually
100-300 amino acid residues in length, which is considered to have the
characteristics of a complete globular protein. A motif is a short
sequence found in otherwise different proteins, which can be as little as
3 residues long (e.g. the RGD cell adhesion motif). The PROSITE database
contains an extensive collection of known motifs and their functions.
More information about the Microbio