Antibiotics for high G+C ratio Gram Positives

Y.E. Knight BMBYEK at
Tue Sep 16 08:38:12 EST 1997

I am looking for antibiotic-resistance genes for use in a high G+C ratio Gram 
Positive, Propionibacterium acnes. In particular I am interested in an 
antibiotic called Bicyclomycin although I cannot find a company who produces 
it commercially. Any ideas? 
In addition, with respect to a resistance gene for this antibiotic, I have
found mention of an E.coli resistance gene, but nothing in Gram Positives.
If anyone has heard, or is working in this area, I would be grateful if you 
could get in touch.

Yolande Knight
bmbyek at

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