Sterne B.anthracis

[I Garsan]

Hi,
A lot of Pharmaceutical Labs are using the Sterne strain of Bacillus 
anthracis for vaccine production because this strain has low virulence 
by its uncapsulated phenotype. My questions are: Can the Sterne strain 
change to capsulated phenotype (so more virulent) through in vivo or in 
vitro pass?. Can shift the haemolysis production or colonial suface 
characteristics be connected with virulence in this strain?.

Kind regards
I.Garsan
 

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