Criticisms of Ames mutagencitiy tests

[Dr. S. Shapiro]

Dear Colleagues;

     I am seeking original articles or reviews describing problems
with the Ames mutagenicity test for prediction of mutagenic or 
carcinogenic activities of chemicals towards mammalian organisms
(particularly though not exclusively humans or human cell lines).
I would appreciate receiving complete citations (author, journal,
volume, page, year) so that I may check out these articles myself.

     Kindly respond to me _directly_ at

                toukie at zui.unizh.ch

Thanks in advance to all responders,

S. Shapiro
toukie at zui.unizh.ch