Criticisms of Ames mutagencitiy tests

[Phil]

Dr. S. Shapiro wrote:
> 
> Dear Colleagues;
> 
>      I am seeking original articles or reviews describing problems
> with the Ames mutagenicity test for prediction of mutagenic or
> carcinogenic activities of chemicals towards mammalian organisms
> (particularly though not exclusively humans or human cell lines).
> I would appreciate receiving complete citations (author, journal,
> volume, page, year) so that I may check out these articles myself.
> 
>      Kindly respond to me _directly_ at
> 
>                 toukie at zui.unizh.ch
> 
> Thanks in advance to all responders,
> 
> S. Shapiro
> toukie at zui.unizh.ch

Please take a look at Bruce Ames comments re. interpretations of
carcinogenicity.