DNA and errors

Penguin penguin at navix.net
Mon Feb 9 17:09:10 EST 1998


Jay Mone' wrote:
> 
> Rob,
> DNA polymerase has an inherent error rate of approximately 10-8, while
> RNA polymerase has an error rate of approx. 10-4.  A large part of the
> difference is due to the lack of prrofreading ability by RNA pol.  DNA
> pol has the ability to check newly synthesized DNA.  If the DNA pol
> detects an error, it can back track, excise the error, and correct it.
> RNA pol lacks this ability.
> 
> Jay Mone'


Doesn't it depend on which DNA polymerase you're talking about? 
Mesophilic, thermophilic, and conditions employed?

Penguin



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