DNA and errors
Gustavo Denarde Nogueira
gutodnog at unincor.br
Thu Feb 12 06:25:47 EST 1998
Penguin escreveu na mensagem <34DF7E86.27F3 at navix.net>...
>Jay Mone' wrote:
>> DNA polymerase has an inherent error rate of approximately 10-8, while
>> RNA polymerase has an error rate of approx. 10-4. A large part of the
>> difference is due to the lack of prrofreading ability by RNA pol. DNA
>> pol has the ability to check newly synthesized DNA. If the DNA pol
>> detects an error, it can back track, excise the error, and correct it.
>> RNA pol lacks this ability.
>> Jay Mone'
>Doesn't it depend on which DNA polymerase you're talking about?
>Mesophilic, thermophilic, and conditions employed?
Yes, it depends on the type I or III, and from the organism it was taken.
There are some commercial types that don't have proofreading too.
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