What is Combinatorial Chemistry?

Dr. Duncan Clark Duncan at nospam.demon.co.uk
Sun May 16 05:37:44 EST 1999


In article <7hkpdh$j8q$1 at remarQ.com>, Jose E. Calderon,P.E.
<jecalderon at cs-engineers.com> writes
>    Is anyone there may explain what is Combinatory Chemistry?

In my simple mind I consider it like:

You find a compound but it has say side effects or say you want to
screen for new compounds starting from a known drug or chemical. What
you basically do is chemically synthesise, on a small scale, in an
automated or semi-automated manner 1000's upon 1000's of derivatives of
the original candidate compound. Each one is then tested for efficacy
etc. The big break-through is through the use of machines that will
accomplish this sort of synthesis in a fraction of the time chemists
took doing it manually. 

Duncan
-- 
The problem with being on the cutting edge is that you occasionally get 
sliced from time to time....

Duncan Clark
DNAmp Ltd.
Tel: +44(0)1252376288
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