How to block/destroy Fc domain of an antibody?

Goran Pavlakovic goran.pavlakovic at
Wed Oct 27 05:13:27 EST 1999

Hi there,

does anybody have an idea how could I block/destroy Fc domain of an
antibody (primary antibody) so that it would not be recognised by
(otherwise) appropriate secondary antibody?

Would incubation with Protein A do the trick?



pavlakovic at

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