website help needed for antibody design

Scott Coutts scott.coutts at
Wed Aug 8 06:09:53 EST 2001

There's a GCG program called 'antigenic' that you might be able to use,
if you have access to it. I think it can be found on BioNavigator
( This is a pay-per-use service, but I think you
get some free time on it before you have to pay. I suppose it depends on
how many times you need to use it!

Anyhow, from the instruction manual:

  "Antigenic looks for  potential antigenic  regions using the method 
   of Kolaskar".


   Kolaskar, AS and Tongaonkar, PC (1990). A semi-empirical method 
   for prediction  of  antigenic  determinants on  protein  
   antigens. FEBS Letters 276, 172-174.

   Parker, JMR, Guo, D and Hodges, RS (1986). Biochemistry 25

"R. Jayakumar" wrote:
> Dear Friends
>      I have a problem. Is there a website that one can go to to find out or
> select the best small region of a
> given protein (as epitope) to be used in the prep of an antibody.  This is
> very urgent.   Any help would be gratefully acknowledged.
> Jayakumar
> ////////////////////////////////////////////////////\\\\\\\\\\\\\\\\\\\\\\\\
> \\\\\\\\\\\\\\\\\\\\\\\\\\\
> R. Jayakumar
> Dept. of Molecular Microbiology,
> School of Biotechnology,
> Madurai Kamaraj University,
> Madurai - 625021. India.
> Tel: +91-452-859141(night hours), +91-452-858471 (Working hours - ask to
> connect to 374)
> Fax:+91-452-859105
> Efax: (603)-688-4665
> Email: jakku at, (send a copy to jakku at ....just in
> case)
> ////////////////////////////////////////////////////\\\\\\\\\\\\\\\\\\\\\\\\
> \\\\\\\\\\\\\\\\\\\\\\\\\\\
> Science is constructed of facts like a house is of bricks, but a mere
> accumulation of facts does not make science nor does a pile of bricks a
> house
> -Henri Poincare
> ---

Scott J. Coutts                 
Bacterial Pathogenesis Research Group
Monash University, Australia
Phone: +61 3 9905 4838       
Email: scott.coutts at 

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