denaturating agarose gel electrophoresis

Urs Lewandrowski Urs.Lewandrowski at ruhr-uni-bochum.de
Fri Nov 16 17:05:05 EST 2001


Hi,

I´m looking for the chemical principle behind denaturating formaldehyde gel
electrophoresis (agarose gels for RNA identification). Does anyone know, how
exactly the formaldehyde interacts with RNA or where the denaturating effect
comes from? A link to tech. lit (primary literature) would be best!

Thanks

Urs Lewandrowski
urs.lewandrowski at ruhr-uni-bochum.de





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