P.aeruginosa and azithromycin

James Lovering james.lovering at pei.sympatico.ca
Mon Sep 10 13:51:08 EST 2001


Can you help, please?

The literature contains several references to the use of azithromycin to
‘reduce' P. aeruginosa's virulence factors and so lessen tissue damage. 
The P aeruginosa is not killed.  

Does the ‘reduction' of virulence factors imply a reduction in the
ability of the bacteria to grow and multiply?  If so does this open the
way to selection of the strains less affected and thus to resistance? 

Thanks

James




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