Yeast-Two-Hybrid System - Some questions
SPAMFILTER-scott.coutts at med.monash.edu.au
Sun Nov 21 18:06:34 EST 2004
There's a lot of papers on this in medline isn't there?
Michael Reiter wrote:
> STAT.......Signal Transducers and Activators of Transcription
> SH2.........Src Homology
> Stats are the only known Transcriptionfactors containing a SH2 domain. Thus
> the Signal transducing pathway is very short, since STATs are directly
> activated by JAKs (Janus Kinases). Jaks are Receptors that do not
> phosphorylate themselves but the STATs. Those STATs recognize each other via
> their SH2 domain for Dimerization. (SH2 domains allow recognition of
> tyrosinphosphates which are generated by the JAKs).
> Hope this helps you!
> "Jorge1907" <jorge1907 at aol.comcomm> schrieb im Newsbeitrag
> news:20041118171718.00480.00000841 at mb-m17.aol.com...
>>I can't help you but would appreciate your explaining the terms:
>>There are more things in heaven and earth, Horatio,
>>Than are dreamt of in your philosophy
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