Help! Nucleotide substitutions

Robert Kuhelj, IJS Robert.Kuhelj at
Fri Aug 20 06:03:39 EST 1993

Hi there,

are there any FTPable computer programs to estimate (calculate) numbers of
synonymous (Ks) and nonsynonymous nucleotide substitutions (Ka)?  

I have already found some articles describing such calculations (e.g. PNAS
vol. 82, p.1741, and Meth. Enzymol. vol. 183, p.544) but I would prefere
this job to be done by computer.


Robert.Kuhelj at

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