Introns length / Chromosomal bands

Laurent Duret duret at evoserv.univ-lyon1.fr
Fri Apr 1 06:33:05 EST 1994


Staining of metaphasic mammalian chromosomes reveals a banding pattern 
(G/R) that reflects structural differences along the chromosome. This 
pattern is known to be correlated with base composition, gene density,
replication timing, chromosome condensation, repeat sequences 
(Craig & Bickmore 1993 BioEssays 15:349-354). 
Uta Francke (in Cell 68:1005-1006) says also that introns from genes
located in G-bands are longer than those located in R bands... but does not 
give any reference.

I am interested in the comparison of the structure of genes in the
different chromosomal compartments. 

Does anyone know an article that illustrates differences in intron/exon
organization between genes from G and R bands?

Thanks for your help.


Laurent Duret

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