Status of selection-induced mutation

SEAN M. HIGGINS HIGGINSS at VAX.CS.HSCSYR.EDU
Mon Jun 13 13:30:50 EST 1994


Hello,

What is the current state of selection-induced mutation work?  The
latest entry in to the literature that I am aware of is Hall (1993);
in which, it is stated:

"At this time, there is not a robust model to account for selection-
induced mutations."

Is this still the case?  Have I missed more recent entries in the
literature?  What is the current thinking/conversation of those
individuals concerned with this topic?

Any help will be greatly appreciated!

Sean M. Higgins
SUNY Health Science Center
higginss at vax.cs.hscsyr.edu

Hall, B. G. 1993. The role of single-mutant intermediates in the
generation of trpAB double revertants during prolonged selection.
J. Bacteriol.  175:6411-6414.



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