Dominance mechanisms - molecular

Tony Long tdlong at
Thu Mar 24 13:18:22 EST 1994

I'm surprised no one mentioned THE CLASSIC paper on this topic with respect
to evolution.  This paper is required reading in most molecular evolution
graduate courses -- or at least should be.  The paper:

Kacer and Burns.  1981.  The molecular basis of dominance.  Genetics 97: 

The paper describes how mutant alleles in an enzyme pathway will
automatically be recessive in nature wholly as a result of the kinetic
properties of enzyme flux.

Tony Long
Center for Population Biology
U. C. Davis
Davis, CA
tdlong at

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