Dominance mechanisms - molecular

John Gillespie john at josquin.ucdavis.edu
Thu Mar 24 16:03:31 EST 1994


Tony Long (tdlong at ucdavis.edu) wrote:
: I'm surprised no one mentioned THE CLASSIC paper on this topic with respect
: to evolution.  This paper is required reading in most molecular evolution
: graduate courses -- or at least should be.  The paper:

: Kacer and Burns.  1981.  The molecular basis of dominance.  Genetics 97: 
: 639-666.

: The paper describes how mutant alleles in an enzyme pathway will
: automatically be recessive in nature wholly as a result of the kinetic
: properties of enzyme flux.

: Tony Long
: Center for Population Biology
: U. C. Davis
: Davis, CA
: tdlong at ucdavis.edu

BUT, the UR_CLASSIC is Wright, S. 1934. Physiological and evolutionary
theories of dominance.  Amer. Nat. 68:25-53.

Kacser & Burns is derivative.




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