Y-linked mammalian clock rates (was: Humans slow mutation rate)

Daniel Weinreich dmw at MCZ.HARVARD.EDU
Mon Apr 17 13:55:29 EST 1995


Ask and ye shall receive! 

This morning I asked how many rounds of DNA replication per generation
occur in mammalian germ lines.  I further speculated that if the Y-linked
clock runs faster it must be the case that male germline cells undergo
more rounds of DNA replication per generation than do female germline
cells. 

An authority on precisely the question of Y-linked mammalian clock rates,
who cites several references regarding the number germline DNA replication
per generation in mammals kindly writes as follows: 

>From GSBS005%UTSPH.THENET at lib.tmc.edu Mon Apr 17 13:58:34 1995
>Date: Mon, 17 Apr 95 12:48:13 CDT
>From: GSBS005%UTSPH.THENET at lib.tmc.edu
>To: dmw at mcz
>
>My colleagues and I have published some data on these issues.
>The references can be found in the following papers and the references 
>therein: Shimmin et al. Nature 362, 745, 1993; Chang et al. PNAS 91, 827,
>1994; and Chang and Li, J. Mol. Evol. 40, 70, 1995.
>Best regards,   Wen-Hsiung Li

Happy reading everyone, and thank you Dr. Li.

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