Comparing Sequences: on PCs?

Peter.DeRijk derijkp at
Mon Jul 31 07:25:40 EST 1995

Tom DeVrie (tomdevrie at wrote:
: Are programs for comparing base-pair sequences available on Macs or PCs,
: rather than only on Unix work stations?

: Four years ago, I took a grad course in mol. evoln. at Oregon State. 
: There, we used Unix-based programs for comparing sequences and
: constructing trees.  Now, I am participating in a summer program in mol.
: biol. for high school teachers.  My final project will be designing a
: evolution/mol. biol./ stratigraphy/radiometric dating integrative elective
: course.  One part of the course will be to take Genbank sequences from
: related organisms (e.g., cetaceans) and establish their similarity.  For
: mtDNA sequences of 250-350 bp, this could be done crudely by hand, but
: program that aligns sequences, assigns color codes to nucleotides, etc. 
: would be more appealing to students, not to mention more efficient and
: powerful.

There is DCSE (Dedicated Comparative Sequence Editor) for DOS. It does what 
you want, though the Unix versions are a lot nicer. You might consider 
using Linux to run Unix programs on your PC. You can find more info on and
the distributions of DCSE on URL:
or use anonymous ftp to host

: Thanks for any help that can be offered.

: Tom DeVries

Peter De Rijk

Peter De Rijk			derijkp at
<a href="">Peter</a>

To achieve the impossible, one must think the absurd.
to look where everyone else has looked, but to see what no one else has seen.

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