DNA vs amino acid sequences

Peter peter at carrot.mcb.uconn.edu
Thu Jun 15 08:56:37 EST 1995


In article <3rn1np$f0m at service1.uky.edu>, clscha00 at ukcc.uky.edu says...
>
>Well, then, why not use DNA sequences that do not actually encode 
>proteins?
>
>

Part of the codon bias reflects a nucleotide bias that is also observed in 
non protein encoding regions of the genome. For example in Giardia the 
third codon positions and the rRNA genes are high in GC's; in chloroplasts 
the third codon positions and the rRNA are AT rich. An easy way to exclude 
the nucleotide and/or codon bias is to use amino acid sequences.

-- 
********************************************
  J. Peter Gogarten
  University of Connecticut
  Dept. Molecular and Cell Biology
  75 North Eagleville Rd.
  Storrs, CT 06269-3044
  USA
  E-Mail: gogarten at uconnvm.uconn.edu 
**********************************************




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