In article <3pae4j$pnv at mserv1.dl.ac.uk>, gsteiner at zoo.univie.ac.at. wrote:
> Can anyone in this forum explain the principles of "spectral
> analysis" of sequence data? Is there any biological significance in
> this method?
>> Hoping for most enlightening replies!
> X Dr. Gerhard Steiner X X==========================X
> X Institute of Zoology X X Voice: +43 1 31336/1299 X
> X University of Vienna X X FAX: /700 X
> X Althanstr. 14 X X==========================X
> X A-1090 VIENNA AUSTRIA X
The clearest example of its application to date is by Lento, Hickson,
Chambers, and Penny (MBE 12:28-52. 1995.) I suggest that you particularly
study Figure 3 in that article. Note also that a LogDet (log determinant)
transformation of the data does an amazing job of increasing the
frequency of pairwise comparisons that support a particular
hypothesis. Sorry this is not much of an explanation of the method
but I'm not sure I could do that in 30 words or less.
Doug Eernisse <DEernisse at fullerton.edu>
Dept. Biological Science MH282
California State University
Fullerton, CA 92634