QU: spectral analysis

Doug Eernisse DEernisse at fullerton.edu
Tue May 16 12:52:45 EST 1995


In article <3pae4j$pnv at mserv1.dl.ac.uk>, gsteiner at zoo.univie.ac.at. wrote:

> Can anyone in this forum explain the principles of "spectral 
> analysis" of sequence data? Is there any biological significance in 
> this method?
> 
> Hoping for most enlightening replies!
> 
> Gerhard
> 
> 
>    X========================X
>    X  Dr. Gerhard Steiner   X         X==========================X 
>    X  Institute of Zoology  X         X Voice:  +43 1 31336/1299 X
>    X  University of Vienna  X         X   FAX:             /700  X
>    X  Althanstr. 14         X         X==========================X
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>       
>            

Hi Gerhard!

The clearest example of its application to date is by Lento, Hickson,
Chambers, and Penny (MBE 12:28-52. 1995.) I suggest that you particularly
study Figure 3 in that article. Note also that a LogDet (log determinant)
transformation of the data does an amazing job of increasing the
frequency of pairwise comparisons that support a particular
hypothesis. Sorry this is not much of an explanation of the method
but I'm not sure I could do that in 30 words or less.

Doug

-- 
Doug Eernisse <DEernisse at fullerton.edu>
Dept. Biological Science MH282
California State University
Fullerton, CA 92634



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