sequence homology inference

Winston Hide hide at maspar.com
Sat Nov 18 13:04:16 EST 1995


In article <Pine.PMDF.3.91.951110082911.539480474A-100000 at crcvms.unl.edu>,
bjadams at CRCVMS.UNL.EDU wrote:

> Concerning  the Determination of Homologous Sequences,
> David Maddison wrote:
 there's
> <just nothing to get a hold of."
> 
>Try the concept of looking at grouped content.

More similar sequence will by nature of both DNA and peptide sequence 
have simlar frequencies of n-plets. 

Clustering according to this method can produce remarkably accurate
distance measures, but if the data is simply divergent protein noise,
then a more rigorous di-peptide freequency analysis could provide
some help. Basically though noise in noise out.

Win

-- 
All views are via telescope...



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