DNA substitutions saturated?

Joe Felsenstein joe at evolution.genetics.washington.edu
Wed Nov 29 18:20:10 EST 1995


In article <carmean-2911951219520001 at berbee.botany.ubc.ca>,
Dave Carmean <carmean at sfu.ca> wrote:
>Any suggestions for the best (and hopefully simplest) way to discover if
>the substitutions in my DNA alignment are saturated?
>
>I can use DNAdist (PHYLIP) to find the rates of substitution between taxa
>and Hillis's g1 test to indicate that the data set is not random.  Neither
>of these directly address the question of saturation.

Wouldn't being _really_ saturated be the same as looking like a random and
unrelated sequence?  If so, your test rejecting randomness would already have
rejected true saturation.

-----
Joe Felsenstein         joe at genetics.washington.edu     (IP No. 128.95.12.41)
 Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA



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