10Sa RNA-Genetic Code Evol.

Jeffrey J. Huckaby huckabyj at minerva.cis.yale.edu
Sat Apr 6 19:58:20 EST 1996

Does anyone have any insight as to the implications of 10Sa RNA on the 
evolution of the genetic code?
FYI:  10Sa RNA contains a tRNA-like structure with an analine attached 
and a mRNA-like sequence which adds a degradation signal sequence to 
truncated mRNAs that are stalled during translation...

I think that it is hard to decide whether or not 10Sa RNA is a fossil 
from the RNA world or if it is a derived mechanism for eliminating 
abberant proteins....

If 10Sa RNA is ancient, then what does the coupling of a tRNA- and mRNA- 
molecule say about the evolution of protein synthesis in general and more 
specifically about the evolution of the genetic code?  


"Full of questions and devoid of answers!" 

Jeff Huckaby                                                      Jeff Huckaby
Department of Biology						       426 OML
email huckabyj at minerva.cis.yale.edu                            Yale University
office:(203) 432-3877               		  	   New Haven, CT 06511
WWW http://www.yale.edu/~huckabyj/topbio.html     	    Lab:(203) 432-3982

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