fixation of deleterious alleles?

Chris Colby colby at bio.bu.edu
Fri Apr 12 10:14:59 EST 1996


Chris Colby (colby at bio.bu.edu) wrote:
: The probability of fixation of a neutral allele is 1/2N (for diploids)
: and (approx.) 2s for slightly beneficial alleles. Does anyone know the
: probability of fixation for a deleterious allele?

Never mind, I found it: u = (2s)/(1-e^-4Ns). Works for both positive and 
negative s as long as the absolute value of s is small.

Chris Colby --- email: colby at biology.bu.edu or colby at acs.bu.edu ---
"'My boy,' he said, 'you are descended from a long line of determined,
resourceful, microscopic tadpoles--champions every one.'"
 	--Kurt Vonnegut from "Galapagos"





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