enzymes/evolution

Jose M. Bautista jbautist at hgmp.mrc.ac.uk
Thu Apr 18 15:04:34 EST 1996


On 1 Apr 1996 elida at parasit.lan.mcgill.ca wrote:

> I am interested in published examples of proteins which have the same function
> and do not share primary structures homology and vice-versa, in the context
> of evolution. If someone could direct me to such references I will appreciate.
> Elida
> 
> 
> 
Elida,

Try to contact with Janet Thorton at the Birbeck College, University 
College of London. Her group have set up a database grouping the folds of 
3D structures of proteins. You can find there a 7% of identity between 
two proteins (viral and plant) which share the very same structure.

I am not sure about this address: cath at biochem.ucl.ac.uk, but it could be 
the right one.

Good luck

Jose

 



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