Codon Bias

Jeffrey J. Huckaby huckabyj at minerva.cis.yale.edu
Wed Feb 7 10:25:18 EST 1996


	I am interested in codon bias as a combinatorial optimization 
problem...in some organisms, "optimal" codon usage appears to be 
correlated with the level of gene expression--highly expressed genes use 
the optimal codons whereas genes with lower expression use rare codons.  
Essentially, I am interested if this pattern results from a complex 
optimization process?

	Does anyone know of any articles on this issue?
Thanks in Advance
Jeff


==============================================================================
Jeff Huckaby                                                      Jeff Huckaby
Department of Biology						       420 OML
email huckabyj at minerva.cis.yale.edu                            Yale University
office:(203) 432-3877               		  	   New Haven, CT 06511
WWW http://www.yale.edu/~huckabyj/topbio.html     	    Lab:(203) 432-3982
==============================================================================





More information about the Mol-evol mailing list