[GCG] Calculating Evolutionary Distances, H

[Lloyd Allison]

galtier at acnuc.univ-lyon1.fr (Nicolas Galtier) writes:

>These distance computation methods differ in the evolutionary model they
>assume to correct for multiple substitutions. Attempts to compare the
>assumed models and to choose the best one for a given data set were made
>only recently (Works of Zarkikh, Yang and Goldman, Rhzetsky and Nei), and no
>standard answer can currently be given.

If you are interested in how accurate inferred distances might be:
   L.Allison, C.S.Wallace,
   The posterior probability distribution of alignments and its application to
   parameter estimation of evolutionary trees and to optimization of multiple
   alignments.
   J. Mol. Evol 39 418-430 1994

Lloyd Allison
Dept. of Computer Science, Monash University, Clayton, Victoria 3168, AUSTRALIA
<A HREF="http://www.cs.monash.edu.au/~lloyd/tildeStrings/">Molecular Biology</A>