robison at nucleus.harvard.edu
Tue Jan 30 13:53:18 EST 1996
Thanks to Larry Moran and Ossi Turunen for sending me the citation.
For future reference, some citations from the Entrez query:
(only 1st author shown)
Occurrence in humans and guinea pigs of the gene related to
their missing enzyme L-gulono-gamma-lactone oxidase.
Arch Biochem Biophys 267, 842-6 (1988)
Molecular basis for the deficiency in humans of gulonolactone oxidase,
a key enzyme for ascorbic acid biosynthesis.
Am J Clin Nutr 54, 1203S-1208S (1991)
Guinea pigs possess a highly mutated gene for L-gulono-gamma-lactone
oxidase, the key enzyme for L-ascorbic acid biosynthesis missing in
J Biol Chem 267, 21967-72 (1992)
Cloning and chromosomal mapping of the human nonfunctional gene for
L-gulono-gamma-lactone oxidase, the enzyme for L-ascorbic acid
biosynthesis missing in man.
J Biol Chem 269, 13685-8 (1994)
Department of Molecular & Cellular Biology
Department of Genetics
robison at mito.harvard.edu
More information about the Mol-evol