Vit C

Keith Robison robison at nucleus.harvard.edu
Tue Jan 30 13:53:18 EST 1996


Thanks to Larry Moran and Ossi Turunen for sending me the citation.
For future reference, some citations from the Entrez query:
(only 1st author shown)

http://atlas.nlm.nih.gov:5700/htbin-post/Entrez/query?uid=89104405&form=6&db=m&Dopt=m


Nishikimi, 1988 
     Occurrence in humans and guinea pigs of the gene related to 
     their missing enzyme L-gulono-gamma-lactone oxidase. 
     Arch Biochem Biophys 267, 842-6 (1988)

Nishikimi, 1991 
     Molecular basis for the deficiency in humans of gulonolactone oxidase, 
     a key enzyme for ascorbic acid biosynthesis. 
     Am J Clin Nutr 54, 1203S-1208S (1991)

Nishikimi, 1992 
     Guinea pigs possess a highly mutated gene for L-gulono-gamma-lactone 
     oxidase, the key enzyme for L-ascorbic acid biosynthesis missing in 
     this species. 
     J Biol Chem 267, 21967-72 (1992)

Nishikimi, 1994 
     Cloning and chromosomal mapping of the human nonfunctional gene for
     L-gulono-gamma-lactone oxidase, the enzyme for L-ascorbic acid 
     biosynthesis missing in man. 
     J Biol Chem 269, 13685-8 (1994)


Keith Robison
Harvard University
Department of Molecular & Cellular Biology
Department of Genetics 

robison at mito.harvard.edu 






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