"microsatellites"

dermitzakis at nefeli.imbb.forth.gr dermitzakis at nefeli.imbb.forth.gr
Sat Feb 1 18:19:06 EST 1997


In article <5cnhjm$g0v at mserv1.dl.ac.uk>, "Boris Martchenko" <bomar at rva.stud.pu.ru> writes:
>Hi all:
>
>Could anyone tell me who is the author of term "microsatellites" and is it
>the same that "simple sequences"?
>(refers is appreciated)
>
>Thanks,
>Boris
>


I do not really know where the term comes from.
However they are short tandem repeats in contrast to minisatellites which are
long. A alternative name is SSTR (simple sequence tandem repeats) or VNTR
(variable number tanden repeats). They are called --satellites because they
were supposed to be located in satellite DNA (heterochromatin). On the contrary
they are dispersed all over the genome (even in coding regions; e.g. gene for 
the Huntington disease: Huntingtin) of every organism (even in chloroplasts
sometimes). Apart from that they do not have to be polymorphic to be called
microsatellites.

Manolis Dermitzakis
Department of Biology,
University of Crete
GREECE.



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