Making alignments

Sean Eddy eddy at wol.wustl.edu
Tue Jan 20 16:03:57 EST 1998


In article <6a30e6$ro7 at net.bio.net> "Guy A. Hoelzer" <hoelzer at med.unr.edu> writes:
  >This seems to me to be an overly optimistic view of the value of maximum
  >likelihood approaches.  In general, maximum likelihood is vulnerable to
  >errors in the chosen model of evolution and in the parameter estimates
  >that are used.

Agreed. But on the other hand: a phylogenetic inference method that is
/not/ sensitive to the chosen model of evolution would be...? 

-- 

- Sean Eddy, Ph.D. 
- Dept. of Genetics, Washington University School of Medicine
- 660 S. Euclid Box 8232, St. Louis MO 63110, USA 
- mailto://eddy@genetics.wustl.edu http://genome.wustl.edu/eddy




More information about the Mol-evol mailing list