selective sweep etc

Rcjohnsen rcjohnsen at aol.com
Mon Apr 19 12:50:17 EST 1999


<< Subject: selective sweep etc
From: Martin Cann <mjcann at med.cornell.edu>
Date: Mon, Apr 5, 1999 3:57 PM
Message-id: <7eami6$fiq at net.bio.net>

Dear all,

I am a postdoc working on a family of tandemly repeated genes in the
male germline.  I wish to understand how these duplications can occur
and become fixed in the genome and have come across references that
mention selective sweep, reduced recombination rates etc.

Can anyone please recommend a good text or series of references that can
give me a scholarly but preferably non-mathematical review of the
subject matter.

Many thanks.

Martin Cann

Department of Pharmacology
Weill Medical College of Cornell University

mjcann at med.cornell.edu
 >>


I dont' know if the book is still in print but it was a good book.  It is
Evolution by Gene Duplication by Susimo Ohno 1970 Springer Verlag New
York.Heidleberg.Berlin

or you may find something in the website Evolution-A multilevel feedback
system(esp in gain of function) at
http://www.catalase.com/evolve.htm#gainfun

or a Cornell page  at
http://www.bio.cornell.edu/biochem/calvo/biobm232/lecture/lecture17/lectur
e17.html
This page shows the mechanism for tandem duplication.

hope this helps
Regards,
Roger J.





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