LAMARC: update of migrate (version 0.7)
beerli at genetics.washington.edu
Thu Jun 3 19:32:50 EST 1999
An updated version of MIGRATE (0.7) is available on our web-site
MIGRATE estimates effective population sizes and past migration rates
between n populations. The migration model can be chosen to be a
n-island migration model, stepping stone models or full migration matrix
models with asymmetric migration rates and different subpopulation sizes.
The maximum likelihood parameter estimation is based on the coalescent with
The input data can be either non-recombining sequence data, microsatellite
data, or electrophoretic allele data. Output can be the maximum likelihood
estimates, profile-likelihood curves for each parameter,
likelihood-ratio tests, and summary plots.
MIGRATE is part of the LAMARC package developed by
Mary K. Kuhner, Jon Yamato, Peter Beerli and Joe Felsenstein.
[LAMARC == Likelihood Analysis with Metropolis Algorithm using Random Coalescence]
LAMARC is a package of programs for computing population parameters,
such as population size, population growth rate and migration rates by
using likelihoods for samples of data (sequences, microsatellites,
and electrophoretic polymorphisms) from populations. It approximates the
summation of likelihood over all possible gene genealogies that could
explain the observed sample. The programs are memory-intensive but can
run effectively on workstations or modern microcomputers. The package is
continually expanding and more executables for different machines will
Currently, there are four programs available: coalesce, fluctuate,
migrate, and recombine.
Peter Beerli <beerli at genetics.washington.edu>
University of Washington, GENETICS, Box 357360, Seattle,
WA 98195-7360, USA. Work:(206) 543-8751,
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