IUBio

Why only DNA or RNA bears the genetic information?

Mary K.Kuhner mkkuhner at kingman.genetics.washington.edu
Fri Dec 29 13:25:48 EST 2000


In article <92ik31$pbe$1 at mercury.hgmp.mrc.ac.uk>,
Takahiko Ishiguro  <isiguro at home.email.ne.jp> wrote:
>In all living things on the earth, only DNA or RNA bears the genetic
>information$B!"(Band the central dogma should be only way to express the
>information out to a phenotype.

>I believe that it is not mystery or unusual even if signs of some trials in
>the process of the evolution remain in our world here.  However, we cannot
>find out the exception. I wonder why the glimpse of the evolution is not
>found.

It might be difficult to recognize non-nucleotide life if we did
encounter it.  After all, the vast majority of bacterial species were not
detectable until PCR allowed us to see things that cannot be
cultured; and PCR will not find non-nucleotide life.

Even in conventional life I think there are a few exceptions or
near-exceptions to the central dogma.  Several organisms including
paramecia and flies "inherit" forms of positional information without
involvement of the nucleus, and the conformation of prions is
"inherited" by protein-protein transmission.

Mary Kuhner mkkuhner at genetics.washington.edu


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