What is a mutation?

Angela Merlo angela.merlo at ioez.tu-freiberg.de
Thu Sep 21 04:04:14 EST 2000


Hi everyone in this newsgroup.
Maybe you think that my question is very simple, but for me is not very
clear.
I research the adaptation of one bacteria to grow in a media (with
chlorbenzoate) where normaly it can=B4t grow. It seems for me that there
is not  enzymatic regulation but a "mutation", so changes in the genome.=20
I would say that: if there are changes in the genome, then there is a
mutation. After making some experiments, it look like it could have
been  a reorganisation in the chromosome, homologous recombination,
insertion...=20
That is: the genes for degrading CB are already in the cell, but somehow
not expressed untill they move to an appropiate place in the chromosome.
I haven=B4t finish my experiments but I guess that there is a reversion,
and if I culture the "mutant" again in a rich medium they loose the
ability to grow in CB.=20
Can I say it is a genome regulation?, an adaptive mutation?, a
mutation?... Is there any exact definition accepted by the mayority of
scientific community?
Any clue?

Thanks

Angela


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