parametric bootstrapping

John Harshman harshman.diespamdie at sjm.infi.net
Sat Feb 3 18:27:36 EST 2001


In article <95f402$dnh$1 at mercury.hgmp.mrc.ac.uk>, Andrea Hansen
<webmaster at bioinformatik.de> wrote:

> Hi,
> 
> could somebody explain the difference between normal bootstrapping 
> and parametric bootstrapping when constructing phylogenetic trees?

Normal bootstrapping (non-parametric bootstrapping) involves resampling
the real data set, with replacement, to produce a number of
pseudoreplicate data sets. Parametric bootstrapping involves estimating
evolutionary parameters from the real data, and then using those
parameters to evolve characters on an assumed tree to produce
pseudoreplicates. In both cases, the pseudoreplicates are then compared to
the real data set in some way, which varies depending on what you are
trying to test.

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