Measures of non-synonymous substitutions

James McInerney james.o.mcinerney at may.ie
Mon Dec 15 12:28:26 EST 2003


Hi folks,

Could anybody tell me if there is a substantial difference between
estimating the rate of change in second positions of codons as a measure of
non-synonymous substitution rate versus using some of the other methods of
estimating this rate?

All changes in second positions are non-synonymous, therefore it should be a
reasonable estimate of the rate of fixation of non-synonymous substitutions
(although there are other positions where non-synonymous substitutions occur
also).

Best,


James

---



More information about the Mol-evol mailing list