[Molecular-evolution] Re: Quantitating the degree of conservation
(by gilbertd from bio.indiana.edu)
Sun Jan 31 20:39:59 EST 2010
THe various protein databases do clustering of genes.
You might want to use the number of species or gene copies in a gene cluster
as a measure of convervation. E.g. Uniprot's UniRef data set.
(max 5,345 genes at 50% identity)
(max 23 genes at 50% id)
On 2010-01-27, Sidney Cambridge <cambridge from ana.uni-heidelberg.de> wrote:
> Dear all,
> I hope my question is not too trivial....
> I am looking for a quantitative measure of the degree of genetic
> conservation - basically attaching a high value to highly conserved
> genes such as histones and low values to genes that are not very
> conserved. Ideally there would be a database for all genes of the
> mouse or human genome with a 'conservation' value for each gene.
> Does something like this exist ?
> Thank you very much in advance !
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