Protein structure from scratch?

Douglas C Pearson dopearso at magnus.acs.ohio-state.edu
Thu Aug 11 11:29:13 EST 1994


Floeckner Hannes <floeckn at wst.edvz.sbg.ac.at> wrote:
>I wonder what you mean with '65% accurate model'. This "percentage correct"
>measure is, as far as I know, always used in connection with algorithms for
>the prediction of secondary structure (like the EMBL prediction server, xy%
>of the residues assigned the correct secondary structure). But these secondary
>structure predictions don't give a 3D model of the protein.
>By the way, I don't think 65% is a good result.

i believe the connection with secondary structure is correct (though i'd be 
happy if somebody could confirm that for me...i'm just a second-year grad 
student, for pete's sake!).  i agree, that's not the best model in the world,
but if it's a choice between knowing something about a protein's secondary/
tertiary structure and knowing nothing, what are you going to take?

this type of modeling is good as a starting point.  nothing more.

but thanks for the response anyway.

chuck
-- 
"clueless chuck" aka douglas c pearson jr -- dopearso at magnus.acs.ohio-state.edu
osu biophysics program -- bio113 teaching assistant at large -- married 1 year!
whowillHealthewoundedskiespoliticsterrifyteardowntheCompromiseliveforlovemortal



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