Recognizing structural conservation

jherndon at jherndon at
Wed Sep 14 15:20:38 EST 1994

>Is there / is anyone aware of a program that can recognize structurally
>conserved regions in proteins? The input should be something like two 
>PDB files.

See this recent mini-review for programs and pointers:

Holm, L.; Sander, C. "Searching Protein Structure Databases has Come
of Age" Proteins 1994, 19, 165-173.

It have the info you need and get you started.

Jeff Herndon
Res. Asst. Prof.
Dept. of Medicinal Chemistry
Medical College of Virginia / Virginia Commonwealth Univ.

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