correlated mutations

[Aare Abroi]

Hallo !

I have a question about correlated mutations. For example is it possible to
find amino-acids which are involved in receptor-ligand interaction by
analyzing receptor and ligand protein families  (I mean the some receptor or
ligand sequences from different organisms). The complementary surfaces may
by mirrored in correlated mutations in sequences. If there are some programs
which do this work could you please let me know.




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       Aare Abroi                 Estonian Biocentre 
     aabroi at ebc.ee                    Riia 23
  tel. +372 7 420 223              Tartu, EE2400
  fax: +372 7 420 286                 Estonia