From Heather.Vincent from manchester.ac.uk  Mon Feb  2 16:31:30 2009
From: Heather.Vincent from manchester.ac.uk (Heather Vincent)
Date: Mon Feb  2 20:49:21 2009
Subject: [Molecular-modelling] Molecular Modelling and Structure-based Drug
	Design - deadline reminder
Message-ID: <49876632.4070904@manchester.ac.uk>

This is a reminder for those people considering taking our online
course, which begins again in March 2009.

The application deadline is 13 February.  However, it is advisable to
apply before the deadline to allow time for any questions in processing
your application.

I have included the course outline below; the full details are on our
website
(http://octette.cs.man.ac.uk/bioinformatics/modules/bs6251.html).  If
you have any questions, or need advice on the module options, please
contact Heather.Vincent@manchester.ac.uk

This course is divided into 7 sections as follows:-

1.    Molecular Mechanics
     a. The molecular potential energy function
     b. The empirical force field
     c. Sources of force field data
     d. Some examples of important force fields

2.     Energy Minimisation
     a. First derivative techniques: steepest descent and conjugate 
gradients
     b. Second derivative techniques: Hessian matrix and Newton-Raphson
     c. Global optimisation (simulated annealing, Tabu search, genetic
algorithms)

3.     Molecular Dynamics and Monte Carlo Simulations
     a. Brief introduction to statistical mechanics
     b. Molecular dynamics simulations
     c. Monte Carlo simulations

4.     Conformational Analysis
     a. Systematic methods
     b. Random search methods
     c. Distance geometry
     d. Molecular dynamics

5.     Solvation
     a. Brief comparison of different solvation methods
     b. Periodic boundary conditions

6.     Calculation of Thermodynamics Parameters
     a. Difficulties with thermodynamics calculations
     b. Free energy perturbation method

7.     Structure-Based Drug Design
     a. Predicting protein-biomolecule structures
     b. The search problem
     c. Virtual screening
     d. Conformational flexibility

The coursework requires some experience in programming.  If you do not 
have this experience, our course 'Introduction to software development 
in Java' 
(http://octette.cs.man.ac.uk/bioinformatics/modules/bs6250.html) would 
be a suitable preparation.

From shanbiogene from gmail.com  Mon Feb 16 07:04:44 2009
From: shanbiogene from gmail.com (shan)
Date: Mon Feb 16 13:07:25 2009
Subject: [Molecular-modelling] Summer Training
Message-ID: <b43ea5ef-b6ed-43ce-bc35-2080dc607e5c@w1g2000prm.googlegroups.com>

NeoGen Bio Solutions Offer Summer Project & Intensive industrial
training Program

Special features:

=95 Special job opportunities for training students at NeoGen
=95 Guidance for PhD & studies in abroad
=95 Hands on training on commercial softwares in addition to the
training program

Intensive Industrial Training Program Duration 15 days:

=95 Introduction to Bioinformatics
=95 Genomic tools and databases
=95 Immunoinformatics
=95 Metabolomics
=95 Microarray Data Analysis.
=95 Molecular Modeling and Drug Design
=95 Perl Programming
=95 Proteomic tools and Databases
=95 Python Programming
=95 Structural Bioinformatics

Summer Project+Traning 1 Month:

=95 BIOTOOLS AND SOFTWARES
=95 BIOPROGRAMMING
=95 DATABASE CREATION
=95 GENOMICS
=95 PROTEOMICS
=95 STRUCTURAL BIOLOGY
=95 DRUG DESIGNING
=95 COMPUTATIONAL BIOLOGY

NeoGen Biosolutions,
12, M.E.S.Road, Ganapathipuram
(Behind Madras Christian College)
East Thambaram, Chennai-59
9094019566, 9094019577