Are any mushrooms known to contain hydroxylamines?
Bruce A. Caldwell
caldwelb at fsl.orst.edu
Mon Aug 13 03:57:20 EST 2001
Hydroxamate-based siderophores (specific iron chelators) are widely produced
by fungi, including mycorrhiza-formers and wood-rotters. Bacteria generally
produce catechol-based siderophores, although there are a few exceptions.
Oregon State University
Corvalls OR 97331-5752
bruce.caldwell at orst.edu.
John Chalmers wrote:
> I'd like to know too. Hydroxylamine and its simple alkyl derivatives are
> laboratory mutagens-- I've used it and methoxylamine in the past to
> mutate Neurospora conidia back in the Pleistocene when I was a fungal
> geneticist. I believe they react with cytosine to form an adduct that
> mispairs with Adenine instead of the normal Guanine, but I'd have to
> look it up this AM.
> Salicylhydroxamic acid is respiratory inhibitor in Neurospora and other
> organism, probably, IIRC, by chelating iron in the respiratory chain.
> Some bacteria produce hydroxamic acid derivatives to scavenger iron and
> I see no reason why fungi might not also.
More information about the Mycology