Significance of string of histidines in membrane protein?

Tony Zador zador-anthony at CS.YALE.EDU
Wed Sep 9 11:50:17 EST 1992


A newly cloned K channel w/>70% homology to other K channels has a
string of ~10 histidines on the cytoplasmic side, and elsewhere a
string of 6 again on the cytoplasmic side. 

Can anyone suggest any significance to this sequence? What proteins
other than histones have a similar arrangement?

Thanks,
Tony Zador



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