William E. White bwhite at
Tue Nov 16 15:57:22 EST 1993

In article <1993Nov3.191327.105566 at> skgtljh at (Lewis J Herberg) writes:
>A phencyclidine-semsitive site responds to
>various toxic and/or recreational compounds including ketamine, a
>well-known cough mixture,

Actually the binding sites for PCP (or ketamine, or MK801, or DXM) are
confusing and evidently far from understood.  In addition to a binding
site (PCP1) that blocks NMDA channels, there is also the sigma site, as 
well as a potential PCP2 site, which may be a reuptake site.

|  Bill White   +1-614-594-3434     | bwhite at             |
|  31 Curran Dr., Athens OH  45701  | bwhite at (alternate) |
|  SCA: Erasmus Marwick, Dernehealde Pursuivant, Dernehealde, Middle Kingdom  |

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